Idiopathic autoimmune thrombocytopenic purpura

Childhood ITP occurs in acute and chronic forms. In general, both diseases are mild and can be managed conservatively. Approaches to therapy are highly controversial and vary widely among pediatricians and academic centers. Approximately 5% of children with ITP will develop chronic disease with seve...

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Bibliographic Details
Published inAdvances in pediatrics Vol. 41; no. 1; pp. 111 - 134
Main Authors Kurtzberg, J, Stockman, 3rd, J A
Format Journal Article
LanguageEnglish
Published United States 1994
Subjects
Acute Disease
Adrenal Cortex Hormones - therapeutic use
AIDS/HIV
Child
Child, Preschool
Chronic Disease
Combined Modality Therapy
Diagnosis, Differential
Female
HIV Infections - complications
Humans
Immunoglobulins - therapeutic use
Infusions, Intravenous
Male
Purpura, Thrombocytopenic, Idiopathic - complications
Purpura, Thrombocytopenic, Idiopathic - diagnosis
Purpura, Thrombocytopenic, Idiopathic - immunology
Purpura, Thrombocytopenic, Idiopathic - therapy
Risk Factors
Severity of Illness Index
Splenectomy
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Summary:Childhood ITP occurs in acute and chronic forms. In general, both diseases are mild and can be managed conservatively. Approaches to therapy are highly controversial and vary widely among pediatricians and academic centers. Approximately 5% of children with ITP will develop chronic disease with severe thrombocytopenia and bleeding. These children require therapy, which is often expensive and not without risk of development of late adverse effects.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
ISSN:0065-3101
DOI:10.1016/S0065-3101(24)00092-6