The metabolism of [ 14C]urea by control and starved Richardson's ground squirrels

1. 1. Richardson's ground squirrels which were starved and water deprived for 1 wk expired one-fifth as much [ 14C]CO 2 during the first 4 hr after injection of [ 14C]urea as control animals. 2. 2. Starvation and water deprivation decreased the gastrointestinal microflora by three-fold and decr...

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Published inComparative biochemistry and physiology. A, Comparative physiology Vol. 69; no. 3; pp. 551 - 555
Main Authors Bintz, Gary L, Torgerson, Gordon E
Format Journal Article
LanguageEnglish
Published Elsevier B.V 1981
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Summary:1. 1. Richardson's ground squirrels which were starved and water deprived for 1 wk expired one-fifth as much [ 14C]CO 2 during the first 4 hr after injection of [ 14C]urea as control animals. 2. 2. Starvation and water deprivation decreased the gastrointestinal microflora by three-fold and decreased the total urease activity by 14-fold. 3. 3. Although 14C from [ 14C]urea was incorporated to a greater extent into lipids and proteins of starved, water-deprived ground squirrels, the extent of incorporation was insufficient to suggest that urea nitrogen is incorporated into tissue metabolites in sufficient quantities to relieve the osmotic load on the kidney.
ISSN:0300-9629
DOI:10.1016/0300-9629(81)93018-8