Psychostimulant effect of synthetic dermorphin analog
The effect of a dermorphin analog on learning was studied in a Wistar rat model of the complex food-seeking task. The preparation decreased the degree of anxiety in a dose-independent manner. In a dose of 50 μg/kg it increased the number of "well"-learning rats by intensifying the learning...
Saved in:
Published in | Bulletin of experimental biology and medicine Vol. 126; no. 3; pp. 866 - 868 |
---|---|
Main Authors | , , , |
Format | Journal Article |
Language | English |
Published |
New York
Springer Nature B.V
01.09.1998
|
Subjects | |
Online Access | Get full text |
Cover
Loading…
Summary: | The effect of a dermorphin analog on learning was studied in a Wistar rat model of the complex food-seeking task. The preparation decreased the degree of anxiety in a dose-independent manner. In a dose of 50 μg/kg it increased the number of "well"-learning rats by intensifying the learning process in rats with initially suppressed cognitive activity. In a dose of 150 μg/kg, the opioid decreased the number of "well"-learning rats due to disturbance of motivation mechanisms, which was manifested in behavioral instability.[PUBLICATION ABSTRACT] |
---|---|
ISSN: | 0007-4888 1573-8221 |
DOI: | 10.1007/BF02447359 |