Growth-inhibitory activity of bone marrow cells during CCl4-induced liver cirrhosis
During CCl^sub 4^-induced liver cirrhosis, cells of the hemopoiesis-inducing microenvironment in the bone marrow of BALB/c mice produced activity inhibiting the growth of erythropoiesis and granulomonocytopoiesis precursors. Stimulation with yeast polysaccharide zymosan increased the inhibitory acti...
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| Published in | Bulletin of experimental biology and medicine Vol. 127; no. 6; pp. 587 - 589 |
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| Main Authors | , |
| Format | Journal Article |
| Language | English |
| Published |
New York
Springer Nature B.V
01.06.1999
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| Subjects | |
| Online Access | Get full text |
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| Abstract | During CCl^sub 4^-induced liver cirrhosis, cells of the hemopoiesis-inducing microenvironment in the bone marrow of BALB/c mice produced activity inhibiting the growth of erythropoiesis and granulomonocytopoiesis precursors. Stimulation with yeast polysaccharide zymosan increased the inhibitory activity (especially in relation to granulomonocytic precursors). The highest growth-inhibitory activity was produced by the bone marrow adherent fraction (residual bone marrow macrophages). Tumor necrosis factor-α is probably responsible for the inhibition of the growth of myeloid precursors in mice with CCl^sub 4^-induced liver cirrhosis.[PUBLICATION ABSTRACT] |
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| AbstractList | During CCl^sub 4^-induced liver cirrhosis, cells of the hemopoiesis-inducing microenvironment in the bone marrow of BALB/c mice produced activity inhibiting the growth of erythropoiesis and granulomonocytopoiesis precursors. Stimulation with yeast polysaccharide zymosan increased the inhibitory activity (especially in relation to granulomonocytic precursors). The highest growth-inhibitory activity was produced by the bone marrow adherent fraction (residual bone marrow macrophages). Tumor necrosis factor-α is probably responsible for the inhibition of the growth of myeloid precursors in mice with CCl^sub 4^-induced liver cirrhosis.[PUBLICATION ABSTRACT] |
| Author | Zubakhin, A. A. Kutina, S. N. |
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| Cites_doi | 10.1111/j.1365-2141.1982.tb01944.x 10.1016/S0268-960X(95)90014-4 10.1002/jcp.1041570318 10.1002/jcb.240550404 |
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| DOI | 10.1007/BF02433285 |
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| References | Y. Abuamer (BF02433285_CR6) 1994; 55 D. N. Mayanski (BF02433285_CR8) 1993; 74 BF02433285_CR1 T. Nagao (BF02433285_CR11) 1995; 20 A. N. Parker (BF02433285_CR12) 1995; 9 BF02433285_CR2 I. A. Orlovskaya (BF02433285_CR5) 1996; 5 H. Mayani (BF02433285_CR7) 1993; 157 E. D. Zanjani (BF02433285_CR13) 1982; 50 S. C. Moore (BF02433285_CR10) 1992; 20 B. Meyerick (BF02433285_CR9) 1991; 1388 S. A. Ketlinskii (BF02433285_CR4) 1995; 3 A. A. Zubakhin (BF02433285_CR3) 1992; 114 |
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| Title | Growth-inhibitory activity of bone marrow cells during CCl4-induced liver cirrhosis |
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