Development of a New Non-dispersed Infrared Analyzer for 13C Breath Test

• Published in: RADIOISOTOPES Vol. 51; no. 6; pp. 237 - 243
• Main Authors: TAKATORI, Kazuhiko, KAJIWARA, Masahiro, CHIYODA, Takeshi, ISHII, Toshihiro, YAMAZAKI, Masao
• Format: Journal Article
• Language: Japanese
• Published: Japan Radioisotope Association 2002
• Subjects: carbon-13 breath test; Golay cell; non-dispersed infrared analyzer
• ISSN: 0033-8303; 1884-4111
• DOI: 10.3769/radioisotopes.51.237

A new small infrared analyzer for 13C breath tests was developed by using a Golay cell as a nondispersed detector. This analyzer, equipped with an automatic sampling system, does not require a thermoregulator and liquid nitrogen. By the device of the optical system and the piping, the measurement became possible in the amount of one sample of 100mL. Moreover, the measurement time of a one-set sample, which consists of two samples, was able to be carried out within 8 min. The reproducibility was S.D. ≤ Δ 0.8 ‰, and the linearity of Δ ‰ value measured by this analyzer was good as compared with IRMS In measurement of breath samples, the correlation between Δ ‰ value measured by this analyzer and those measured by MS was also good, when CO2 concentration is more than 2.5%.