Cellular origin of prealbumin in the rat

The synthetic rate of prealbumin and albumin in primary monolayer cultures of rat hepatocytes was measured by immunochemical methods. The isolated hepatocytes synthesized these proteins in the same ratio as that previously found for the whole body synthesis in vivo. It is concluded that the hepatocy...

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Bibliographic Details
Published inBiochimica et biophysica acta Vol. 716; no. 3; pp. 446 - 449
Main Authors Felding, Peter, Fex, Göran
Format Journal Article
LanguageEnglish
Published Netherlands 16.06.1982
Subjects
Animals
Cells, Cultured
Kinetics
Liver - metabolism
Prealbumin - biosynthesis
Rats
Rats, Inbred Strains
Serum Albumin - biosynthesis
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ISSN0304-4165
0006-3002
DOI10.1016/0304-4165(82)90040-X

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Summary:The synthetic rate of prealbumin and albumin in primary monolayer cultures of rat hepatocytes was measured by immunochemical methods. The isolated hepatocytes synthesized these proteins in the same ratio as that previously found for the whole body synthesis in vivo. It is concluded that the hepatocytes synthesize the main part of prealbumin in the rat.
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ISSN:0304-4165
0006-3002
DOI:10.1016/0304-4165(82)90040-X