Aflatoxins, B1, B2, G1, G2 in primary liver cell carcinoma

Aflatoxin B1, B2, G1, G2 levels were determined in sera of 20 patients with primary liver cell carcinoma (CC). Values of B1 above 0.15 microgram/ml were obtained in sera of three patients. Hepatitis B surface antigen (HBsAg) was detected in only 35% of patients. 50-90% of serum levels were cleared i...

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Bibliographic Details
Published inToxicology letters Vol. 10; no. 2-3; p. 309
Main Authors Onyemelukwe, G C, Ogbadu, G H, Salifu, A
Format Journal Article
LanguageEnglish
Published Netherlands 01.02.1982
Subjects
Adult
Aflatoxin B1
Aflatoxins - blood
Aflatoxins - toxicity
Carcinoma, Hepatocellular - blood
Female
Hepatitis B virus - pathogenicity
Humans
Liver Neoplasms - blood
Liver Neoplasms - etiology
Male
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Summary:Aflatoxin B1, B2, G1, G2 levels were determined in sera of 20 patients with primary liver cell carcinoma (CC). Values of B1 above 0.15 microgram/ml were obtained in sera of three patients. Hepatitis B surface antigen (HBsAg) was detected in only 35% of patients. 50-90% of serum levels were cleared in 24 h in three patients studied. Although it is inconclusive as to the carcinogenic potential of aflatoxins in adult man, foodstuffs should be protected from excessive aflatoxin contamination.
ISSN:0378-4274
DOI:10.1016/0378-4274(82)90093-5