Longitudinal melanonychia associated with hydroxyurea therapy in a patient with essential thrombocytosis

Occurrence of skin lesions during long‐term therapy with hydroxyurea are well described, but there have been only a few case reports of longitudinal melanonychia associated with hydroxyurea treatment. We report herein longitudinal melanonychia associated with hydroxyurea therapy in a subject with es...

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Bibliographic Details
Published inJournal of the European Academy of Dermatology and Venereology Vol. 13; no. 2; pp. 137 - 139
Main Authors Cohen, Arnon D., Hallel‐Halevy, Dafnah, Hatskelzon, Lev, Peretz, Eyal, Halevy, Sima
Format Journal Article
LanguageEnglish
Published Oxford, UK Blackwell Publishing Ltd 01.09.1999
Subjects
Aged
Essential thrombocytosis
Female
Humans
Hydroxyurea - adverse effects
Hydroxyurea therapy
Melanins - analysis
Melanonychia
Melanosis - chemically induced
Nail Diseases - chemically induced
Thrombocytosis - drug therapy
Time Factors
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Summary:Occurrence of skin lesions during long‐term therapy with hydroxyurea are well described, but there have been only a few case reports of longitudinal melanonychia associated with hydroxyurea treatment. We report herein longitudinal melanonychia associated with hydroxyurea therapy in a subject with essential thrombocytosis. The prolonged time lapse (1‐year) between initiation of hydroxyurea therapy and the onset of the longitudinal melanonychia should be noted.
ISSN:0926-9959
1468-3083
DOI:10.1111/j.1468-3083.1999.tb00868.x