Constituintes químicos e avaliação da atividade antibacteriana de Macroptilium lathyroides (L.) Urb. (Fabaceae)

The chemical investigation of the stems and branches of Macroptilium lathyroides led to the isolation of a mixture of β-sitosterol and stigmasterol. The extracts from the roots allowed the isolation of lasiodiplodin, a mixture of stigmast-4-en-6β-ol-3-one and stigmast-4,22-dien-6β-ol-3-one, de-O-met...

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Published inQuímica Nova Vol. 36; no. 9; pp. 1370 - 1374
Main Authors Sousa, Leôncio M. de, Gois, Roberto W. da S., Lemos, Telma L. G., Arriaga, Ângela M. C., Andrade-Neto, Manoel, Santiago, Gilvandete M. P., Braz-Filho, Raimundo, Costa, José G. M. da, Rodrigues, Fabiola F. G.
Format Journal Article
LanguageEnglish
Published Sociedade Brasileira de Química 2013
Subjects
coumaronochromone
lasiodiplodin derivatives
Macroptilium lathyroides
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Summary:The chemical investigation of the stems and branches of Macroptilium lathyroides led to the isolation of a mixture of β-sitosterol and stigmasterol. The extracts from the roots allowed the isolation of lasiodiplodin, a mixture of stigmast-4-en-6β-ol-3-one and stigmast-4,22-dien-6β-ol-3-one, de-O-methyllasiodiplodin, genistein and lupinalbin A. The structures of the isolated compounds were assigned on the basis of their NMR data, including comparison of their spectral data with values described in the literature. The antibacterial activity of crude extracts from stems, branches and roots was evaluated. This is the first report involving the chemical investigation of this species.
ISSN:0100-4042
1678-7064
DOI:10.1590/S0100-40422013000900016