A Review on Plant-Derived Immunomodulatory Agents: Hopes as an Alternative Medicine in the Management of Immune-Related Disorders

In humans, the immune system serves as a protective barrier against infection; however, when the immune system is out of balance, it can harm the host. Immunomodulators are chemicals or medications that have been employed in the clinic to treat an unbalanced immune response. The majority of immunolo...

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Bibliographic Details
Published inTraditional and integrative medicine Vol. 8; no. 2
Main Authors Deva, K. Deepa, Bose, B. Vanitha, Basavan, Duraiswamy
Format Journal Article
LanguageEnglish
Published Tehran University of Medical Sciences 27.06.2023
Subjects
Cytokines
Immune system
Immunomodulators
Interferons
T cells
Tumor necrosis factor
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Summary:In humans, the immune system serves as a protective barrier against infection; however, when the immune system is out of balance, it can harm the host. Immunomodulators are chemicals or medications that have been employed in the clinic to treat an unbalanced immune response. The majority of immunological medicines in clinical use are cytotoxic. They harm the patient's quality of life by causing various side effects and being associated with higher production costs, longer lead times, and a high failure rate. Furthermore, obtaining single-compound chemicals with low toxicity, high efficacy, and selectivity for specified disorders is difficult for researchers. As a result, techniques based on alternative medicine are gaining attraction in drug development, focusing on innovative natural compounds utilized to treat various disorders. Many plant molecules founded to have biologically beneficial properties. This review aimed to look at the immunomodulatory activity of plant-derived chemicals from widely-used plants.  
ISSN:2476-5104
2476-5112
DOI:10.18502/tim.v8i2.13085