Functional dyspepsia: from pathogenesis to therapeutic aspects

Functional dyspepsia (FD) is one of the most common gastroenterological diseases. The article presents modern views on the pathogenesis of the disease. It is shown that disorders of motor skills (retardation of voiding function, disturbance of relaxation accommodation) and stomach sensitivity (visce...

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Bibliographic Details
Published inMedicinskij sovet no. 3; pp. 18 - 25
Main Authors Dicheva, D. T., Subbotina, Yu. S., Bektemirova, L. G., Andreev, D. N.
Format Journal Article
LanguageEnglish
Russian
Published Remedium Group LLC 12.05.2019
Subjects
eradication
functional dyspepsia
helicobacter pylori
prokinetics
proton pump inhibitors
rebamipide
rome iv criteria
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Summary:Functional dyspepsia (FD) is one of the most common gastroenterological diseases. The article presents modern views on the pathogenesis of the disease. It is shown that disorders of motor skills (retardation of voiding function, disturbance of relaxation accommodation) and stomach sensitivity (visceral hypersensitivity to stretching) are considered to be one of the main pathophysiological mechanisms of FD. The authors present a modern algorithm of treatment of patients with FD, based on the clinical recommendations of the Rome Consensus IV revision (2016) and the Russian Gastroenterological Association (2017). The strategy of differentiated use of pharmaceuticals for different variants of FD is considered.
ISSN:2079-701X
2658-5790
DOI:10.21518/2079-701X-2019-3-18-25