The role of matrix metalloproteinases in the myocardial remodeling

• Published in: CardioSomatika Vol. 11; no. 3; pp. 22 - 28
• Main Authors: Bazylev, Vladlen V., Kanaeva, Tatyana V.
• Format: Journal Article
• Language: English
• Published: Concilium Medicum 25.11.2020
• Subjects: matrix metalloproteinases; myocardial remodeling; сhronic heart failure

The main structural event in the development of heart failure is the myocardial remodeling. The extracellular matrix, that was knows as, considered an inert framework of cardiomyocytes, plays an important role in cardiac remodeling. The enzyme system, primarily responsible for the degradation of the...