NOVEL DIRECTION IN ADHERENCE ASSESSMENT — FOCUS ON THE GERIATRIC SYNDROMES

• Published in: Kardiovaskuli͡a︡rnai͡a︡ terapii͡a︡ i profilaktika Vol. 16; no. 3; pp. 46 - 51
• Main Authors: Chukaeva, I. I., Larina, V. N., Karpenko, D. G., Larin, V. G.
• Format: Journal Article
• Language: English; Russian
• Published: SILICEA-POLIGRAF» LLC 01.06.2017
• Subjects: остеопороз; пожилой возраст; приверженность лечению; сердечная недостаточность; старческая астения
• ISSN: 1728-8800; 2619-0125
• DOI: 10.15829/1728-8800-2017-3-46-51

Aim. To investigate on the factors determining the adherence to optimal treatment  in older  age  patients  with chronic  heart  failure (CHF) in outpatient setting.Material and methods. Into the open, comparative single-movement non-randomized  study, 80 CHF patients  were included at the age ≥60 y.o. Comparison group consisted  of 40 patients (18 males, 22 females) with non-CHF cardiovascular  disorders.  Patients  underwent  the comorbidity assessment, laboratory and echocardiographic parameters, 6-minute walking test, cognitive status, treatment adherence, bi-photon x-ray absorptiometry. Criteria for frailty were 3 points by FRAIL (Fatigue, Resistance,  Ambulation, Illnesses, Loss of Weight).Results. The adherent to treatment were 40% of CHF patients, and 75% in comparison  group  (p<0,001).  In monofactorial analysis there  was correlation of treatment  adherence with the level of cognition by Mini-mental  State  Examination — odds  ratio  (OR) 1,5;  95%  confidence interval  (CI) 1,2-1,9  (р<0,001),  frailty  — OR 3,5;  95%  CI 1,3-9,5 (р=0,011),  osteoporosis  — OR  2,98;  95%  CI 1,0-8,9   (р=0,050), comorbidity by Charlson — OR 1,21; 95% CI 1,0-1,5 (р=0,050).Conclusion. Adherent to treatment were 40% of outpatients with CHF at the  age  ≥60  y.o.  Multiple comorbidities,  impaired  cognition  status, osteoporosis, frailty influenced negatively the adherence to treatment in older persons with CHF.