Three new cases of R-type virus-like particles in hamster tumours

R-type virus-like particles (VLP) in fibrosarcoma and myeloid tumour induced in hamsters with the myeloleukaemic virus of Graffi and in hamster embryonic fibroblasts infected with the lympholeukaemic virus Ly/Ya are described. The particles are found in the cysternae of the rough surface endoplasmic...

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Bibliographic Details
Published inArchives of virology Vol. 133; no. 3-4; p. 485
Main Authors Roussev, R, Polianova, M, Toshkova, R
Format Journal Article
LanguageEnglish
Published Austria 1993
Subjects
Animals
Cricetinae
Endoplasmic Reticulum - microbiology
Fibroblasts - microbiology
Fibrosarcoma - microbiology
Leukemia Virus, Murine
Leukemia, Experimental - microbiology
Mesocricetus
Microscopy, Electron
Neoplasm Transplantation
Retroviridae Infections - microbiology
Tumor Cells, Cultured
Tumor Virus Infections - microbiology
Virion - isolation & purification
Virion - ultrastructure
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Summary:R-type virus-like particles (VLP) in fibrosarcoma and myeloid tumour induced in hamsters with the myeloleukaemic virus of Graffi and in hamster embryonic fibroblasts infected with the lympholeukaemic virus Ly/Ya are described. The particles are found in the cysternae of the rough surface endoplasmic reticulum (RER). The VLP are classified as endogenous virus (EV) whose expression is determined by the initial infection with murine leukaemia virus (MLV).
ISSN:0304-8608
DOI:10.1007/BF01313786