A Mysterious Rash Following Cardiothoracic Surgery: A Not So Sweet Ending

A male in his 70s, with a recent history of aortic valve replacement, mitral valve repair, and permanent pacemaker implantation (PPM), developed a fever, raised inflammatory markers, and a disseminated rash. Despite being attributed a diagnosis of an unspecified connective tissue disorder and erythe...

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Published inCurēus (Palo Alto, CA) Vol. 16; no. 9; p. e69048
Main Authors Daoud, Ahmad, Rajani, Ronak, Androshchuk, Vitaliy, Montarello, Natalie
Format Journal Article
LanguageEnglish
Published United States Cureus Inc 10.09.2024
Cureus
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Summary:A male in his 70s, with a recent history of aortic valve replacement, mitral valve repair, and permanent pacemaker implantation (PPM), developed a fever, raised inflammatory markers, and a disseminated rash. Despite being attributed a diagnosis of an unspecified connective tissue disorder and erythema nodosum at his local hospital, his symptoms continued to deteriorate. A subsequent urgent admission was arranged to his original cardiothoracic centre for the exclusion of infective endocarditis (IE). Although this was subsequently ruled out by echocardiography and microbiological evaluation, a diagnosis of Sweet syndrome (SS) was made following a punch biopsy of a skin lesion. This was later attributed to myelodysplastic syndrome following a bone marrow biopsy. In this report, we firstly describe our diagnostic algorithm for reaching this diagnosis and the characteristic skin lesions associated with this condition. We furthermore review the history of SS, its known associations, and treatment options.
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ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.69048