Clinical Significance of IgG-rheumatoid Factor in RA Patients
Clinical correlations with IgG-rheumatoid factor (IgG-RF) were evaluated in 41 patients with rheumatoid arthritis (RA). The patients with positive IgG-RF with disease duration of less than two years showed increased levels in ESR, C-reactive protein, serum IgG concentrations and Lansbury's inde...
Saved in:
Published in | Orthopedics & Traumatology Vol. 44; no. 4; pp. 1277 - 1280 |
---|---|
Main Authors | , , , |
Format | Journal Article |
Language | English |
Published |
West-Japanese Society of Orthopedics & Traumatology
1995
|
Subjects | |
Online Access | Get full text |
Cover
Loading…
Summary: | Clinical correlations with IgG-rheumatoid factor (IgG-RF) were evaluated in 41 patients with rheumatoid arthritis (RA). The patients with positive IgG-RF with disease duration of less than two years showed increased levels in ESR, C-reactive protein, serum IgG concentrations and Lansbury's index, but they had neither extra-articular disorders nor vascular damage. However, four of eight patients with positive IgG-RF with disease duration of over five years had extra-articular disorders and vascular damage (especially interstitial pneumonia). In one early RA patient with positive IgG-RF who showed decreased levels of ESR and C-reactive protein and serum IgG concentrations, a high titer of IgG-RF was revealed over six months and joint damage progressed. In conclusion, we suggested that measurment of IgG-RF is useful in the clinical evaluation of rheumatoid arthritis associated with extra-articular disorders, vascular damage, and joint damage progression. |
---|---|
ISSN: | 0037-1033 1349-4333 |
DOI: | 10.5035/nishiseisai.44.1277 |