Simultaneous Determination of Four Substances in Plasma and Dermal Microdialysates of Guinea Pig after Different Acupoints Administration of Fufang Baijiezi Gel

• Published in: Chinese herbal medicines Vol. 7; no. 4; pp. 365 - 370
• Main Authors: Wang, Guo-hua, Zhang, Bao-xian, Nie, Qi-xia, Zang, Chen, Zhu, Qiong
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 01.11.2015
• Subjects: acupoints administration; Fufang Baijiezi Gel; LC-MS; microdialysis; pharmacokinetics; 同时测定; 复方; 物质; 皮肤; 穴位; 给药; 豚鼠; 透析液; pharmacokinetics; acupoints administration; LC-MS; Fufang Baijiezi Gel; microdialysis

Objective To study the pharmacokinetic properties of Fufang Baijiezi Gel（FBG） after different acupoints administration. Methods Sinapine thiocyanate, tetrahydropalmatine, 6-gingerol, and asarinin, which were four substances of FBG, were determined by a sensitive liquid chromatography tandem mass spe...