Effect of a low-protein diet on the immune system in mice

The effect of an 8% casein diet (low-protein diet, LPD) on the immune system in, mice was compared with that of a 27% casein diet (control diet, CD). Serum protein level, body weight gain and DTH responses to Listeria monocytogenes (L.M) were suppressed in LPD-fed mice. Primary plaqueforming cell (P...

Full description

Saved in:
Bibliographic Details
Published inNihon Eiyō, Shokuryō Gakkai shi Vol. 45; no. 3; pp. 249 - 255
Main Authors Yanai, M. (Snow Brand Milk Products Co. Ltd., Kawagoe, Saitama (Japan). Technical Research Inst.), Ohmori, T, Kawanishi, G, Mitsuyama, M
Format Journal Article
LanguageJapanese
Published Japan Society of Nutrition and Food Science 1992
Subjects
DIET
DIETA
E. coli
GENERO HUMANO
GENRE HUMAIN
immune system
IMMUNITE
IMMUNITY
INMUNIDAD
Listeria monocytogenes
low-protein diet
MANKIND
MICE
mouse
PROTEINAS
PROTEINE
PROTEINS
RATON
REGIME ALIMENTAIRE
SOURIS
Online AccessGet full text

Cover

More Information
Summary:The effect of an 8% casein diet (low-protein diet, LPD) on the immune system in, mice was compared with that of a 27% casein diet (control diet, CD). Serum protein level, body weight gain and DTH responses to Listeria monocytogenes (L.M) were suppressed in LPD-fed mice. Primary plaqueforming cell (PFC) responses to SRBC in LPD-fed mice remained low because of suppression of an increase in spleen cell number. There was no effect on natural killer cell activity. A low level of phagocytosis of E. coli B by peritoneal macrophages was observed in LPD-fed mice. The mortality of LPD-fed mice due to primary infection with E. coli B or L.M was slightly lower than that of CD-fed mice, but higher in secondary infection with L.M. These results demonstrate a relationship between undernutrition produced by a low-protein diet and some aspects of the immune system in mice.
Bibliography:S30
9401636
ISSN:0287-3516
1883-2849
DOI:10.4327/jsnfs.45.249