Fluorescent phenylthiazoles: Application as latent fingermark and their cytotoxicity against NOK-SI cell line

Fingerprints are unique to each individual who contributes to human identification in forensic cases. In this sense, the present work aimed to synthesize 1H-pyrazol-1-yl-4-phenylthiazoles and apply them as powder agents to reveal latent finger marks as an alternative and low cost related to powders...

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Published inChemical Data Collections Vol. 33; p. 100700
Main Authors da Rosa, Bruno Nunes, Mariotti, Kristiane de Cássia, Pacheco, Bruna Silveira, da Silva, Caroline Carapina, Carreño, Neftalí Lenin Villarreal, Nicolodi, Caroline, Poletti, Tais, Silva, Allison Carlos Assunção, da Silva, Adriana Fernandes, Giongo, Janice Luehring, Vaucher, Rodrigo de Almeida, de Oliveira, Tiago Franco, de Pereira, Claudio Martin Pereira
Format Journal Article
LanguageEnglish
Published Elsevier B.V 01.06.2021
Subjects
Cytotoxicity
Development powder
Fingermark
Forensic chemistry
Thiazoles
Development powder
Cytotoxicity
Fingermark
Forensic chemistry
Thiazoles
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Summary:Fingerprints are unique to each individual who contributes to human identification in forensic cases. In this sense, the present work aimed to synthesize 1H-pyrazol-1-yl-4-phenylthiazoles and apply them as powder agents to reveal latent finger marks as an alternative and low cost related to powders found on the market. The compounds were characterized by infrared; fluorescence; 1H NMR; 13C NMR; laser diffractometer and SEM. In addition, cytotoxicity was also evaluated in oral keratinocytes showing high cell viability. The result of the hemolytic assay revealed that compound 2a does not present red cell cytotoxicity. The prepared powders were applied to fingermarks deposited on different surfaces providing quality visualization at level three so that human identification is possible. [Display omitted]
ISSN:2405-8300
2405-8300
DOI:10.1016/j.cdc.2021.100700