Correlation of chronic periodontal disease and cardiovascular disease

The aim of the study was to assess correlative risk of progression of inflammatory periodontal lesions, the development of a systemic inflammatory reaction and cardiovascular diseases. The study involved 89 patients with chronic periodontal disease (CPD) of varying degrees. High cardiovascular disea...

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Bibliographic Details
Published inStomatologija (Moskva) Vol. 96; no. 1; p. 4
Main Authors Grudyanov, A I, Tkacheva, O N, Avraamova, T V
Format Journal Article
LanguageRussian
Published Russia (Federation) 2017
Subjects
Adult
Apolipoprotein A-I - blood
Biomarkers - blood
C-Reactive Protein - analysis
Cardiovascular Diseases - blood
Cardiovascular Diseases - epidemiology
Chronic Periodontitis - blood
Chronic Periodontitis - epidemiology
Female
Humans
Interleukin-6 - blood
Male
Middle Aged
Risk Factors
Russia - epidemiology
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Summary:The aim of the study was to assess correlative risk of progression of inflammatory periodontal lesions, the development of a systemic inflammatory reaction and cardiovascular diseases. The study involved 89 patients with chronic periodontal disease (CPD) of varying degrees. High cardiovascular disease risk was revealed in 8.8% of patients with moderate and 13.3% of patients with severe periodontal disease. It is proved that an additional factor contributing to the pathogenic relationship between periodontal inflammatory changes and the development of cardiovascular disease is systemic inflammatory response with increased hrC-reactive protein >3.4 mg/l and interleukin-6 to11.0±3.4 mg/l. Changes of blood lipid spectrum with a reduction in apolipoprotein A1 were associated with progression and development of the CPD. Correlations of somatic and dental pathology requires dentists and cardiologists joint efforts to modify common risk factors.
ISSN:0039-1735
DOI:10.17116/stomat20179614-7