Robust methods for estimating functional connectivity

Noninvasive imaging of functional connectivity refers to statistical inferences about causal interactions in activity across different brain regions observed during rest or while a subject is performing a task. Application of coherence to noisy functional imaging data, like fMRI, with limited number...

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Published inNeuroImage (Orlando, Fla.) Vol. 47; p. S169
Main Authors Nagarajan, S.S., Owen, J.P., Hinkley, L.B., Attias, H.T., Sekihara, K.
Format Journal Article
LanguageEnglish
Published Amsterdam Elsevier Inc 01.07.2009
Elsevier Limited
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Online AccessGet full text
ISSN1053-8119
1095-9572
DOI10.1016/S1053-8119(09)71816-6

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Summary:Noninvasive imaging of functional connectivity refers to statistical inferences about causal interactions in activity across different brain regions observed during rest or while a subject is performing a task. Application of coherence to noisy functional imaging data, like fMRI, with limited number of samples can be quite unreliable. [...]inferring functional connectivity using bivariate methods that neglect the influence of voxels not under consideration can give inconsistent results.
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ISSN:1053-8119
1095-9572
DOI:10.1016/S1053-8119(09)71816-6