Neural correlates of somatosensory stimulation in a healthy subject using fMRI block design vs. event related design

• Published in: NeuroImage (Orlando, Fla.) Vol. 47; p. S109
• Main Authors: Pasaye, Erick H., del Refujio Pacheco, M., Paz Guitierrez, J., Solorzano, S. Alcauter, Mercadillo, R., Barrios, F.A.
• Format: Journal Article
• Language: English
• Published: Amsterdam Elsevier Inc 01.07.2009; Elsevier Limited
• Subjects: Cognition & reasoning; Functional magnetic resonance imaging; Paradigms
• ISSN: 1053-8119; 1095-9572
• DOI: 10.1016/S1053-8119(09)70974-7

A frequently kind of paradigm used in the clinical as well as for investigation is somatosensory paradigms, but in the clinical case you need a very simple design to have an easy task performance and a quickly image process as well as a high statistical significance, the best paradigm design in this case could be the robust Block Design1 (BD) who is the most popular in the cases of somatosensory paradigms but not always in the case of investigation you have to use a block design if you want to get a very fine somatosensory response who has a poor cortical representation for example the case of somatosensory response of some part about lower limb, may be you need some more sensitive design like Event Related Design (ERD).