Complicated Tumor Lysis Syndrome after CVVH Treatment in a Renal Transplantation Patient： One Case Report and Literature Review

• Published in: Cancer biology & medicine Vol. 6; no. 5; pp. 377 - 380
• Main Authors: Liu, Zengbo, Li, Li, Yang, Jianhui, Han, Zhishuang, Ma, Zengyi, Feng, Aimei
• Format: Journal Article
• Language: English
• Published: Heidelberg Tianjin Medical University Cancer Institute and Hospital 01.10.2009; Renal Transplantation Center, No. 456 Hospital of PLA and Special Hospital of Jinan Military Area, Jinan, Shandong 250031, China; China Anti-Cancer Association
• Subjects: continuous veno-venous; Medicine; Medicine & Public Health; Oncology; tumor lysis syndrome; 综合征; 肾移植; 肿瘤细胞; tumor lysis syndrome; continuous veno-venous hemofi ltration; renal transplantation; continuous veno-venous hemofiltration
• ISSN: 1674-5361; 2095-3941; 1868-324X
• DOI: 10.1007/s11805-009-0377-3

Introduction Tumor lysis syndrome （TLS） is a potentially lethal emergency caused by lysed tumor cells, and it frequently occurs in tumors of hematologic origin. Up until now, there has been only one known report published overseas about TLS resulting from post-transplant lymphoproliferative disorder （PTLD）. In 2008, a PTLD patient who had previously undergone renal transplantation was treated in the renal transplantation center of our hospital, and TLS occurred during treatment for PTLD. At the time, no further literature regarding the treatment of post-transplant renal inadequacy complicating TLS was available. So, continuous veno-venous hemofiltration （CVVH） was used to effectively control the progression of TLS. In this article, the experiences gained from our management of this complex case and our analysis, supported by relevant literature, are described.