Syringotropic Lichen Planus: An Unusual Presentation of a Common Dermatosis - A Report of 2 Cases

Lichen planus (LP) is a chronic inflammatory dermatosis that causes plaques and itchy papules on the skin, as well as erosion and ulcers in the mucous membranes. LP is characterized by a dense dermal T-cell infiltration. Perieccrine inflammation can be seen in a variety of dermatoses, but genuine ly...

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Published inCase reports in dermatology Vol. 16; no. 1; pp. 226 - 233
Main Authors Mohaghegh, Fatemeh, Khodashenas, Zohre, Saber, Mina, Sohrabi, Haniyeh
Format Journal Article
LanguageEnglish
Published Switzerland S. Karger AG 24.10.2024
Karger Publishers
Subjects
Case Series
lichen planus
mycosis fungoides
syringotropic lichen planus
Mycosis fungoides
Syringotropic lichen planus
Lichen planus
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Summary:Lichen planus (LP) is a chronic inflammatory dermatosis that causes plaques and itchy papules on the skin, as well as erosion and ulcers in the mucous membranes. LP is characterized by a dense dermal T-cell infiltration. Perieccrine inflammation can be seen in a variety of dermatoses, but genuine lymphocyte permeation of the secretory coil or lymphocytic syringotropism is a rare sign that is typically seen in mycosis fungoides. In this study, we present 2 uncommon instances of lymphocytic syringotropism in LP. Histopathological examination revealed dense T-cell infiltration and lymphocytic involvement of eccrine glands, confirming syringotropism. Lymphocytic syringotropism is an uncommon finding in LP. Its presence broadens the histopathological spectrum of LP and highlights the need to differentiate it from lymphoproliferative disorders like mycosis fungoides.
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ISSN:1662-6567
1662-6567
DOI:10.1159/000541695