A Rare Case of a Nasopharyngeal Pleomorphic Adenoma Mimicking a Nasopharyngeal Carcinoma

Pleomorphic adenoma is the most common benign pathology of the major salivary gland but rare in the minor salivary gland, especially in the nasopharynx, with only a few cases reported in the literature. A 76-year-old lady presented with bilateral nasal blockage for one year secondary to a nasopharyn...

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Published inCurēus (Palo Alto, CA) Vol. 14; no. 11; p. e31269
Main Authors Abdul Razak, Siti Farhana, Abdul Aziz, Mohd Aizat, Wan Hamizan, Aneeza Khairiyah, Anastasius, Elsie Jane
Format Journal Article
LanguageEnglish
Published United States Cureus Inc 08.11.2022
Subjects
Biopsy
Calcification
Cancer
Case reports
Dysphagia
Endoscopy
Epistaxis
Exocrine glands
Medical imaging
Metastasis
Oral cancer
Radiation therapy
Throat cancer
Tumors
Southeast Asia
Malaysia
nasopharyngeal pleomorphic adenoma
pleomorphic adenoma
nasopharyngeal carcinoma
nasopharynx
minor salivary gland tumour
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Summary:Pleomorphic adenoma is the most common benign pathology of the major salivary gland but rare in the minor salivary gland, especially in the nasopharynx, with only a few cases reported in the literature. A 76-year-old lady presented with bilateral nasal blockage for one year secondary to a nasopharyngeal mass. Histopathological examination reported it to be nasopharyngeal carcinoma, but the mass persisted after a course of chemotherapy combined with radiotherapy. Upon repeat biopsy, the mass was found to be a pleomorphic adenoma. The patient underwent nasopharyngectomy without complications and no evidence of recurrence after 18 months of follow-up.
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.31269