Effect of high-flux hemodialysis plus compound-α Ketoacid tablets under humanistic care on calcium-phosphorus metabolism in uremia patients

Uremia (UR) is a terminal renal failure manifestation with a very high risk of death, high-flux hemodialysis (HFHD) is currently the most common treatment for UR in clinical practice. In this study, we analysed the therapeutic efficacy of HFHD plus Compound-α Ketoacid Tablets for UR under humanistic...

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Published inCellular and Molecular Biology Vol. 70; no. 5; pp. 209 - 213
Main Authors Shi, Yafeng, Zhuang, Shanshan, Hu, Leibin, Weng, Yaping
Format Journal Article
LanguageEnglish
Published France 27.05.2024
Subjects
Adult
Aged
Calcium - metabolism
Female
Humans
Male
Middle Aged
Phosphorus
Renal Dialysis - methods
Tablets
Uremia - metabolism
Uremia - therapy
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Summary:Uremia (UR) is a terminal renal failure manifestation with a very high risk of death, high-flux hemodialysis (HFHD) is currently the most common treatment for UR in clinical practice. In this study, we analysed the therapeutic efficacy of HFHD plus Compound-α Ketoacid Tablets for UR under humanistic care. Firstly, we randomised 100 patients with UR into a research group (RG) for HFHD plus Compound-α Ketoacid Tablets therapy and a control group (CG) for HFHD treatment, with both therapies implemented under humanistic care. By way of comparison, we found that the study group had significantly better renal function after treatment and they had a lower inflammatory response. Also, the study group showed lower calcium and phosphorus metabolism and better immune function. Based on these results, we believe that HFHD + Compound-α Ketoacid Tablets under humanistic care have high clinical value.
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ISSN:0145-5680
1165-158X
1165-158X
DOI:10.14715/cmb/2024.70.5.30