Lung Cancer Screening

Lung cancer is a leading cause of cancer death in the United States and globally with the majority of lung cancer cases attributable to cigarette smoking. Given the high societal and personal cost of a diagnosis of lung cancer including that most cases of lung cancer when diagnosed are found at a la...

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Published inSeminars in respiratory and critical care medicine Vol. 43; no. 6; p. 839
Main Authors Lee, Elizabeth, Kazerooni, Ella A
Format Journal Article
LanguageEnglish
Published United States 01.12.2022
Subjects
Early Detection of Cancer
Humans
Lung Neoplasms - diagnostic imaging
Lung Neoplasms - epidemiology
Sputum
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Summary:Lung cancer is a leading cause of cancer death in the United States and globally with the majority of lung cancer cases attributable to cigarette smoking. Given the high societal and personal cost of a diagnosis of lung cancer including that most cases of lung cancer when diagnosed are found at a late stage, work over the past 40 years has aimed to detect lung cancer earlier when curative treatment is possible. Screening trials using chest radiography and sputum failed to show a reduction in lung cancer mortality however multiple studies using low dose CT have shown the ability to detect lung cancer early and a survival benefit to those screened. This review will discuss the history of lung cancer screening, current recommendations and screening guidelines, and implementation and components of a lung cancer screening program.
ISSN:1098-9048
DOI:10.1055/s-0042-1757885