Comparative Evaluation of Normal Saline Gel and Ozone Therapy on Soft and Hard Tissue Health in Dental Implant Surgery

• Published in: Indian journal of dental research Vol. 35; no. 1; pp. 2 - 6
• Main Authors: Dixit, Abhay, Agarwal, Bhaskar, Singh, Kamleshwar, Chand, Pooran, Rao, Jitendra, Mishra, Niraj
• Format: Journal Article
• Language: English
• Published: Mangalore Medknow Publications & Media Pvt. Ltd 01.06.2024; Wolters Kluwer Medknow Publications
• Subjects: Bone loss; Bone surgery; C-reactive protein; crestal bone loss; dental implant; Dental implants; Dental plaque; Gingival index; Inflammation; Ozone; Pain; Plaque index; Statistical analysis; vas
• ISSN: 0970-9290; 1998-3603
• DOI: 10.4103/ijdr.ijdr_591_23

Abstract Aims: To comparatively evaluate the effect of normal saline gel and ozonated saline-ozonated gel (ozone therapy) on pain, inflammation, soft tissue, and crestal bone loss in dental implant surgery. Methods and Material: Forty adult patients scheduled to undergo implant were randomized into two groups: Twenty patients ( n = 20) received ozone therapy and controls ( n = 20) received normal saline and gel during implant placement. Inflammation and pain were noted at days 1 and 7 and 3 month intervals by estimating C-reactive protein (CRP) levels and assessing visual analogue scale (VAS) scores. At 3 months, soft tissue outcomes were noted in terms of plaque index, gingival index, and pocket depth, while crestal bone loss was noted via a radiograph. Results: Mean CRP levels were significantly higher in the control group as compared to that in the case group on day 1 and day 7 follow-ups ( P < 0.05). Mean VAS scores for pain were also lower in the case group as compared to the control group at all follow-ups, but the difference was significant statistically only at day 1 ( P = 0.061). The plaque index was significantly lower in the case group as compared to the control group ( P = 0.011) at final follow-up. No significant difference between two groups was observed for crestal bone loss. Conclusions: Ozone therapy during implant placement was effective in reduction of pain, systemic inflammation, and plaque deposition in dental implant patients.