Quantification of the Distribution of Azelastine HCl/Fluticasone Propionate Nasal Spray in an Anatomical Model of the Human Nasal Cavity

Rationale In vitro evaluations using an anatomical model of the human nasal cavity quantified the distribution of azelastine HCl (AZ) and fluticasone propionate (FP) in a single nasal spray (Dymista) compared to sequential sprays of marketed azelastine (Astelin) and either Flonase or generic flutica...

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Published inJournal of allergy and clinical immunology Vol. 135; no. 2; p. AB218
Main Authors D'Addio, Alexander, PhD, Ruiz, Nancy, MD, Mayer, Michael, PhD, Berger, William E., MD, MBA, FAAAAI, Meltzer, Eli O., MD, FAAAAI
Format Journal Article
LanguageEnglish
Published St. Louis Elsevier Limited 01.02.2015
Subjects
Allergies
Allergy and Immunology
Nose
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Summary:Rationale In vitro evaluations using an anatomical model of the human nasal cavity quantified the distribution of azelastine HCl (AZ) and fluticasone propionate (FP) in a single nasal spray (Dymista) compared to sequential sprays of marketed azelastine (Astelin) and either Flonase or generic fluticasone.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
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ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2014.12.1648