A thiamonomethinecyanine probe for detection of Pb2+ based on transformation from dimer to monomer by aptamer

A simple method based on a thiamonomethinecyanine dye (dye2) and duplex DNA system was constructed to detect Pb 2+ by UV–Vis spectra. The absorption spectra of dye2 show dimers and monomers peak and the monomer–dimer equilibrium could be regulated with environmental change. Duplex DNA as a template...

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Bibliographic Details
Published inChemical papers Vol. 75; no. 4; pp. 1413 - 1419
Main Authors Yu, Li-Jia, Zhao, Han, Zhang, Ying-Lin, Shi, Xiao-Dong, Ding, Chun-Guang
Format Journal Article
LanguageEnglish
Published Cham Springer International Publishing 01.04.2021
Subjects
Biochemistry
Biotechnology
Chemistry
Chemistry and Materials Science
Chemistry/Food Science
Industrial Chemistry/Chemical Engineering
Materials Science
Medicinal Chemistry
Original Paper
Assembly and disassembly
Pb
detection
Thiamonomethinecyanine dye
Dimers and monomers
G-quadruplex
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Summary:A simple method based on a thiamonomethinecyanine dye (dye2) and duplex DNA system was constructed to detect Pb 2+ by UV–Vis spectra. The absorption spectra of dye2 show dimers and monomers peak and the monomer–dimer equilibrium could be regulated with environmental change. Duplex DNA as a template was used to regulate distinct aggregates of cyanine dye in the presence of Pb 2+ . This system shows a specific absorption signal for Pb 2+ detection.
ISSN:2585-7290
1336-9075
DOI:10.1007/s11696-020-01389-7