Intradermal desensitization with human insulin (recombinant DNA) in a patient with severe allergic skin reaction due to insulin

• Published in: Diabetes care Vol. 5 Suppl 2; no. Supplement_2; pp. 165 - 167
• Main Authors: Bachmann, W, Hasche, H, Mehnert, H
• Format: Journal Article
• Language: English
• Published: United States 01.11.1982
• Subjects: Aged; Desensitization, Immunologic; Diabetes Mellitus, Type 1 - complications; Diabetes Mellitus, Type 1 - immunology; Drug Hypersensitivity - therapy; Female; Humans; Insulin - adverse effects; Insulin - immunology; Recombinant Proteins - immunology

This is a case report of a 70-yr-old female patient with a severe allergic skin reaction (necroses) due to insulin injections. Because of insulin dependency, desensitization to insulin was mandatory. For desensitization, a schedule with intradermal injections of increasing insulin concentrations (fr...