Extensive primary oral malignant melanoma: A case report with review of literature

• Published in: Advances in oral and maxillofacial surgery Vol. 6; p. 100274
• Main Authors: Bijou, Walid, Laachoubi, Mohammed, Oukessou, Youssef, Rouadi, Sami, Abada, Reda, Roubal, Mohamed, Mahtar, Mohamed
• Format: Journal Article
• Language: English
• Published: Elsevier Ltd 01.04.2022; Elsevier
• Subjects: Hard palate; Melanocytes; Oral malignant melanoma; Hard palate; Melanocytes; Oral malignant melanoma
• ISSN: 2667-1476; 2667-1476
• DOI: 10.1016/j.adoms.2022.100274

Oral mucosal melanoma is an exceptionally rare tumor with the tendency to metastasize and locally invade tissues more readily than other malignant tumor of the oral cavity. Here we present a case of 53-year-old women patient with chief complaint of a discoloration over the hard palate since 6 months. On the basis of a through clinical and paraclinical assessment, a diagnosis of oral malignant melanoma was evoked. On histopathological and immunohistochemical analysis with S-100 and homatropine methylbromide 45 the diagnosis of malignant melanoma of the had palate was confirmed. •It is essential to maintain a high index of suspicion for any pigmented lesion within oral cavity.•Especially those occurring in high-risk sites such as palate and maxillary gingiva.•Early and correct diagnosis can save the patient's life as it can be very aggressive and invade adjacent areas.•Patients should be well informed and encouraged to carry out self-inspections..