Hemoglobin, Vitamin D, and Lipids in Subclinical Hypothyroid Patients – Do the Anti -Thyroid Autoantibodies Titer Matters?
Hashimoto's thyroiditis, the commonest cause of hypothyroidism has been proposed as a risk factor for atherosclerosis independent of thyroid function. The aim of this study was to investigate whether Hashimoto's thyroiditis validated by their anti-TPO positivity have any effect on hyperlip...
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Published in | Biomedical & pharmacology journal Vol. 10; no. 3; pp. 1175 - 1180 |
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Main Authors | , , , |
Format | Journal Article |
Language | English |
Published |
Bhopal
Biomedical and Pharmacology Journal
2017
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Subjects | |
Online Access | Get full text |
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Summary: | Hashimoto's thyroiditis, the commonest cause of hypothyroidism has been proposed as a risk factor for atherosclerosis independent of thyroid function. The aim of this study was to investigate whether Hashimoto's thyroiditis validated by their anti-TPO positivity have any effect on hyperlipidemia, Hemoglobin, vitamin D independent of thyroid function in newly diagnosed subclinical hypothyroid patients (SCH) subjects with TSH <10µiu/ml. 40 newly diagnosed sch and 40 healthy euthyroid controls were included in this study. based on anti-tpo status, the sch subjects was divided into tpo positive and negative groups. serum lipid, hemoglobin and vitamin d levels were determined and compared between among the tpo positive and negative sch subjects. subjects with and without anti-tpo had significant differences in levels of low-density lipoprotein, total cholesterol, and nonhdl cholesterol. in correlation analysis, anti-tpo showed statistically significant association with hb, ldl and vitamin d. subclinical hypothyroidism with thyroid autoimmunity is associated with a marginal decrease in hemoglobin and elevation in ldl. whether this holds, any bearing on promoting cardiovascular risk needs to be considered further |
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ISSN: | 0974-6242 2456-2610 |
DOI: | 10.13005/bpj/1218 |