C-H amination in the synthesis of N-heterocycles

N-heterocycles are important motifs in natural products and pharmaceuticals. Recently, the transition metal-catalyzed C-H amination has become a subject in the synthesis of N-heterocycles because of use of the readily available starting materials, high efficiency, economy, and practicability of the...

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Bibliographic Details
Published inReports in organic chemistry Vol. 5; p. 1
Main Authors Fu, Hua, Yu, Jipan
Format Journal Article Book Review
LanguageEnglish
Published Macclesfield Dove Medical Press Limited 01.01.2015
Taylor & Francis Ltd
Subjects
Carbon compounds
Chemical bonds
Chemical properties
Copper
Heterocyclic compounds
Ligands
Oxidation
Structure
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ISSN2230-5246
2230-5246
DOI10.2147/ROC.S56037

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Summary:N-heterocycles are important motifs in natural products and pharmaceuticals. Recently, the transition metal-catalyzed C-H amination has become a subject in the synthesis of N-heterocycles because of use of the readily available starting materials, high efficiency, economy, and practicability of the methods. This review summarizes recent advances in the copper, iron, palladium, rhodium, ruthenium, and nickel-catalyzed synthesis of N-heterocycles via C-H amination strategy. Keywords: N-heterocycles, C-H activation, amination, transition metal-catalyzed, synthetic methods
Bibliography:content type line 1
SourceType-Scholarly Journals-1
ObjectType-Review-1
ISSN:2230-5246
2230-5246
DOI:10.2147/ROC.S56037