The lysozyme of the starfish Asterias rubens

On the basis of a partial N‐terminal sequence, Jollès and Jollès [Jollès, J., & Jollès, P. (1975) Eur. J. Biochem.54, 19–23] previously proposed that the lysozyme from the starfish Asterias rubens represents a new form of lysozyme, called type i (invertebrate) lysozyme. Indeed, it differed from...

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Published inEuropean journal of biochemistry Vol. 271; no. 2; pp. 237 - 242
Main Authors Bachali, Sana, Bailly, Xavier, Jollès, Jacqueline, Jollès, Pierre, Deutsch, Jean S.
Format Journal Article
LanguageEnglish
Published Oxford, UK Blackwell Science Ltd 01.01.2004
Subjects
Asterias rubens
Asteroidea
cDNA
invertebrates
lysozyme
Marine
starfish
structure
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Summary:On the basis of a partial N‐terminal sequence, Jollès and Jollès [Jollès, J., & Jollès, P. (1975) Eur. J. Biochem.54, 19–23] previously proposed that the lysozyme from the starfish Asterias rubens represents a new form of lysozyme, called type i (invertebrate) lysozyme. Indeed, it differed from both the types c (chicken) and g (goose) known in other animals, as well as from plant and phage lysozymes. Recently, several proteins belonging to the same family have been isolated from protostomes. Here we report the complete mature protein sequence and cDNA sequence of the lysozyme from Asterias. These sequences vindicate the previously proposed homology between the starfish, a deuterostome, and protostome lysozymes. In addition, we present a structural analysis that allows us to postulate upon the function of several conserved residues.
Bibliography:Asterias
lysozyme
Present address
MNHN, Paris and Minéralogie Cristallographie (LMCP) UMR 7590, Université P & M Curie, Paris (France), pl. Jussieu, case 115, 75252 Paris cedex 05, France.
AY390770
Note
cDNA is available in the GenBank database under accession number
i
.
The nucleotide sequence of the
ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
content type line 23
ISSN:0014-2956
1432-1033
DOI:10.1046/j.1432-1033.2003.03915.x