Systemic distribution of 14C-labeled formaldehyde applied in the root canal following pulpectomy

The systemic distribution of 14C-labeled formaldehyde which had been placed in the root canals of the canines of cats following pulpectomies was studied using liquid scintillation counting and whole-body autoradiographic technique. Radioactive 14C which had been placed in the canals was found in the...

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Bibliographic Details
Published inJournal of endodontics Vol. 15; no. 11; pp. 539 - 543
Main Authors Hata, Gin-ichiro, Nishikawa, Ikuo, Kawazoe, Satoko, Toda, Tadao
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 01.11.1989
Subjects
Animals
Autoradiography
Cats
Dentin Permeability
Dentistry
Formaldehyde - analysis
Formaldehyde - blood
Formaldehyde - urine
Male
Pulpectomy
Root Canal Irrigants - metabolism
Scintillation Counting
Tooth Permeability
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Summary:The systemic distribution of 14C-labeled formaldehyde which had been placed in the root canals of the canines of cats following pulpectomies was studied using liquid scintillation counting and whole-body autoradiographic technique. Radioactive 14C which had been placed in the canals was found in the plasma 30 min after the root canal procedure. The recovery of systemic 14C radioactivity increased with time. In addition, it seemed that approximately 3% of the dose placed in the teeth was excreted in the urine within 36 h. Whole-body autoradiograms indicated extensive concentration of 14C radioactivity in tissue other than those analyzed with the liquid scintillation technique.
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ISSN:0099-2399
1878-3554
DOI:10.1016/S0099-2399(89)80197-9