Drug discovery for ageing: SIMPs, NEDs and screening challenges

Drugs that modulate fundamental mechanisms of ageing offer the promise of substantially improving the health of ageing populations, but innovative approaches to identify and evaluate such ‘gerotherapeutics’ are needed. Drugs that modulate fundamental mechanisms of ageing offer the promise of substan...

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Published inNature reviews. Drug discovery Vol. 23; no. 10; pp. 725 - 726
Main Authors Faragher, Richard G. A., Hartley, Richard C.
Format Journal Article
LanguageEnglish
Published London Nature Publishing Group UK 01.10.2024
Nature Publishing Group
Subjects
Biomedicine
Biotechnology
Cancer Research
Comment
Medicinal Chemistry
Molecular Medicine
Pharmacology/Toxicology
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Summary:Drugs that modulate fundamental mechanisms of ageing offer the promise of substantially improving the health of ageing populations, but innovative approaches to identify and evaluate such ‘gerotherapeutics’ are needed. Drugs that modulate fundamental mechanisms of ageing offer the promise of substantially improving the health of ageing populations, but innovative approaches to identify and evaluate such ‘gerotherapeutics’ are needed.
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SourceType-Scholarly Journals-1
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ObjectType-News-3
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ISSN:1474-1776
1474-1784
1474-1784
DOI:10.1038/d41573-024-00087-3