The evaluation of M-TRAP technology in detection of ABO groups and its subgroups and its efficacy as a point-of-care test for blood grouping

• Published in: Global journal of transfusion medicine Vol. 6; no. 2; pp. 150 - 155
• Main Authors: Patel, Tarak, Shah, Sangita, Bhatnagar, Nidhi, Shah, Mamta, Tripathi, Sujata, Soni, Shital, Mathew, Ashly, Ahuja, Tejal
• Format: Journal Article
• Language: English
• Published: Wolters Kluwer - Medknow Publications 01.07.2021; Wolters Kluwer Medknow Publications
• Subjects: abd pad; abo grouping; abo subgroups; m-trap technology; ABO subgroups; ABO grouping; M-TRAP technology; ABD pad
• ISSN: 2468-8398; 2455-8893
• DOI: 10.4103/gjtm.gjtm_4_21

Background and Objectives: Accurate ABO blood grouping including detection of subgroups is a core component in transfusion medicine to prevent adverse transfusion reactions. This article highlights the importance of using M-TRAP technology in a pad-based platform as a point-of-care test for offsite blood donation camps, pre release of blood bags from blood center and at patient's bedside for rapid evaluation of blood groups as compared to conventional methods. Methods: ABD-PAD works on principal of membrane trapping technology used for the evaluation of blood group and their subgroup as a point of care test. Result: Total 1,03,987 blood group test were performed, of which 71,885 of patients' and 32,102 of donors' by EMT (Model - QWALYS 3, Manufacturer - Diagast, France). Among them, 4516 blood group discrepancies were detected. Out of 4516 blood group discrepancies, 17 (00.38%) group discrepancies were due to ABO subgroups. Among them, 13 (76.47%) were subgroup A and 4 (23.53%) were subgroup B. These subgroups were detected by M-TRAP technology. Conclusion: The use of M-TRAP technology (ABD PAD) is a reliable method for manual blood grouping and is useful to detect blood group at patient's bedside, outside blood donation camp, and at the time of issue of blood from blood center.