Wound contraction effect of Bermuda grass (Cynodon dactylon) topical cream on induced second-degree burn in male albino mice

• Published in: Journal of medical and allied sciences Vol. 10; no. 1; pp. 3 - 8
• Main Authors: Rallos, Judee, Caballero, Shanine, Codilla, Diana, Mendez, Racealle, Obediente, Alyssa, Samson, Rhiel, Sevillano, Bea, Valle, Rhea, Villaranda, Jude, Denney, Brian
• Format: Journal Article
• Language: English
• Published: Hyderabad Deccan College of Medical Sciences 01.01.2020
• Subjects: Albinism; Antibiotics; bermuda grass; Burns; cynodon dactylon; Flavonoids; Laboratory animals; Medical research; Renaissance period; silver sulfadiazine; Stainless steel; topical cream; wound contraction; Wound healing
• ISSN: 2231-1696; 2231-170X
• DOI: 10.5455/jmas.57824

The study aimed to determine the effectiveness of Bermuda grass (Cynodon dactylon) topical cream on induced second-degree burns in male albino mice by utilizing a randomized controlled trial experimental research design. The research subjects were assigned randomly into three (3) groups and each containing six (6) mice. Silver sulfadiazine was applied on Group 1 while Base cream was applied on Group 2, and five percent (5%) Bermuda grass topical cream was applied on the Group 3. All treatments were applied every twenty-four (24) hours thereafter while measurement of wound contraction began twenty-four (24) hours after the induction of the burn and every forty-eight (48) hours thereafter until the seventeenth day where complete wound contraction was observed. The study supported the potential of Bermuda grass as a possible alternative for Silver sulfadiazine in the treatment of burn injuries. This was demonstrated by a higher mean (%) wound contraction - 93.14±4.59, effect of five percent (5%) Bermuda grass topical cream against the mean percent (%) wound contraction effect of Silver sulfadiazine and Base cream - 78.77±8.98 and 89.38±4.24 respectively.