Anterior atlantoaxial subluxation with Down syndrome and arthritis: case report

Down syndrome (DS) occurs when an individual has a full or partial extra copy of chromosome 21 and is the most common of all malformation syndromes. Associating with numerous pathologies like anterior atlantoaxial subluxation (AAAS) which is an increase in the space between the anterior arch of the...

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Bibliographic Details
Published inJournal of spine surgery (Hong Kong) Vol. 4; no. 4; pp. 803 - 809
Main Authors Prada, Carlos Andres Ferreira, Sanchez Paez, Maria Gabriela, Martinez Amado, Andreina
Format Journal Article
LanguageEnglish
Published China AME Publishing Company 01.12.2018
Subjects
Case Report
platybasia
Down syndrome (DS)
basilar impression
basilar invagination
juvenile chronic arthritis (JCA)
craniovertebral junction (CVJ)
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Summary:Down syndrome (DS) occurs when an individual has a full or partial extra copy of chromosome 21 and is the most common of all malformation syndromes. Associating with numerous pathologies like anterior atlantoaxial subluxation (AAAS) which is an increase in the space between the anterior arch of the first cervical vertebra (C1) and the odontoid process of the second vertebra (C2), most of the time its asymptomatic, only 1-2% to all the 30% who may have the AAAS and DS develop clinical symptoms. In this occasion, we present the case of a patient with SD and Juvenile chronic arthritis (JCA) who has atlantoaxial subluxation of approximately 11mm, basilar impression and platybasia with severe medullary compression in 2 points, requiring surgical management by the Neurological Surgery Service in Bucaramanga-Colombia.
ISSN:2414-469X
2414-4630
DOI:10.21037/jss.2018.12.07