The changes in cyclic alternating pattern(CAP) of epilepsy patients

• Published in: Sleep medicine Vol. 14; p. e69
• Main Author: Baklan, B.
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 01.12.2013
• Subjects: Neurology; Sleep Medicine
• ISSN: 1389-9457; 1878-5506
• DOI: 10.1016/j.sleep.2013.11.134

The aim of this study was to determine the changes in the polysomnographic parameters and the cyclic alternating pattern (CAP) in generalized and partial epilepsy patients (with and without epileptiform discharges on EEG) using video–EEG–PSG recording. 73 patients diagnosed with epilepsy and 19 healthy controls within the same age group (control group) underwent an 8-hour long sleep video–EEG–PSG recording. After the first evaluation, the CAP parameters were scored in 57 patients (31 generalized and 26 partial epilepsy) and 16 healthy subjects who had no sleep diseases and the results were compared within the groups. The total sleep time and the NREM I phase were found to be longest in the partial epilepsy group and shortest in the control group, while the REM phase was found to be exactly the opposite to this. The mean CAP ratios were found to be statistically higher in the generalized epilepsy group when compared to the other two groups. This difference was also found in the control group and the generalized epileptic patients who had no abnormality on EEG. No difference was found between the partial epilepsy and the control group regarding CAP ratios. Patients with generalized epilepsy have differences compared to healthy individuals regarding the macro- and micro-structure of sleep, and it seems that these differences are independent from the epileptiform discharges. In partial epilepsy patients, no microstructural differences were detected, while macrostructural changes were evident. we thanks to Our Sleep technicians Ýlkay,Samime,Ummü and our patients.Support for this study were excluded.