L-Tryptophan-based pyrene conjugate for intracellular zinc-guided excimer emission and controlled nano-assembly

This article describes intracellular zinc-induced excimer emission and tuning of self-assembly from L-tryptophan-pyrene conjugate (1). The zinc-guided excimer formation is due to the interaction of the pyrene moiety in an excited state. AFM studies show the structural modification in the supramolecu...

Full description

Saved in:
Bibliographic Details
Published inAnalytical methods Vol. 16; no. 33; pp. 5633 - 5641
Main Authors Asthana, Surabhi, Maddeshiya, Tarkeshwar, Tamrakar, Arpna, Kumar, Praveen, Garg, Neha, Pandey, Mrituanjay D
Format Journal Article
LanguageEnglish
Published England Royal Society of Chemistry 22.08.2024
Subjects
Conjugates
Emission
Emissions
Excimers
Intracellular
NMR
Nuclear magnetic resonance
Pyrene
Self-assembly
Titration
Tryptophan
Water analysis
Water sampling
Zinc
Online AccessGet full text

Cover

More Information
Summary:This article describes intracellular zinc-induced excimer emission and tuning of self-assembly from L-tryptophan-pyrene conjugate (1). The zinc-guided excimer formation is due to the interaction of the pyrene moiety in an excited state. AFM studies show the structural modification in the supramolecular nano-assembly of 1 from dome-shaped to porous surface after complexation with zinc ions. Further, the interaction of 1 with Zn(II) ion is also studied using DFT, Job's plot, NMR titration and HRMS. The results of Zn(II) ion determination in natural water samples and RAW 264.7 cells demonstrate the practical utility of 1.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1759-9660
1759-9679
1759-9679
DOI:10.1039/d4ay00979g