A study to assess efficacy of lower dose ketamine in labor analgesia and its effect on maternal and perinatal outcome
Background: Present study is planned to study the effectiveness of lower dose ketamine in labor analgesia and its effect on progression of labor, maternal and perinatal outcome.Methods: After obtaining ethical approval from institutional ethical committee, a prospective randomized interventional cas...
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Published in | International Journal of Reproduction, Contraception, Obstetrics and Gynecology Vol. 7; no. 11; p. 4521 |
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Main Authors | , |
Format | Journal Article |
Language | English |
Published |
International Journal of Reproduction, Contraception, Obstetrics and Gynecology
01.11.2018
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Subjects | |
Online Access | Get full text |
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Summary: | Background: Present study is planned to study the effectiveness of lower dose ketamine in labor analgesia and its effect on progression of labor, maternal and perinatal outcome.Methods: After obtaining ethical approval from institutional ethical committee, a prospective randomized interventional case control study was conducted in Department of obstetrics and gynecology, N.S.C.B medical college, Jabalpur. Parturient in active labor without risk factors were given 0.2 mg/kg intravenous ketamine in bolus form and 0.1 mg/kg in maintenance dose at 30 minutes interval till full dilatation and the results were analyzed using VAS scale and WHO partogram.Results: In present study, 280 parturient were included in the study. In 140 cases, induction-delivery interval was shortened in 47.10% cases. Pain relief was satisfactory (VAS 2-8) in 77.90% cases. However, 80.70% cases had transient light headedness. Overall satisfaction was significantly high in the intervention group (P<0.001). Conclusions: A lower dose ketamine in bolus form with loading dose of 0.2 mg/kg followed by maintenance dose of 0.1 mg/kg could provide safe and acceptable analgesia during labor and delivery.Keywords: APGAR, Ketamine, Labor analgesia, Maternal outcome, Perinatal outcome |
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ISSN: | 2320-1770 2320-1789 |
DOI: | 10.18203/2320-1770.ijrcog20184500 |