Synthesis of new 2-substituted 3-(tri(di)fluoromethyl)-quinoxalines from 3-(trifluoromethyl)quinoxalin-2(1H)-oneand 3-(tri(di)fluoromethyl)quinoxaline-2-carboxylic acids

• Published in: Chemistry of heterocyclic compounds (New York, N.Y. 1965) Vol. 51; no. 3; pp. 259 - 268
• Main Authors: Didenko, Andrey V., Vorobiev, Mikhail V., Sevenard, Dmitri V., Sosnovskikh, Vyacheslav Ya
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.03.2015
• Subjects: Chemistry; Chemistry and Materials Science; Organic Chemistry; Pharmacy; quinoxalin-2; 2-substituted 3-(tri(di)fluoromethyl)-quinoxalines; quinoxaline-2-carboxylic acid; thione; quinoxaline-2; one

Starting from 3-(trifluoromethyl)quinoxalin-2(1 H )-one, a wide range of new 2-substituted 3-(trifluoromethyl)quinoxalines were obtained, including amino, bromo, chloro, hydrazino, phenyl, α-furyl, formyl, methylsulfanyl, and methylsulfonyl derivatives. 3-(Tri(di)-fluoromethyl)quinoxaline-2-carboxyl...