Oral pemphigus vegetans: a case report

Pemphigus is a rare vesiculobullous autoimmune disease that exhibits blistering of the skin and oral cavity. It is caused by autoantibodies directed against antigens on the surface of keratinocytes. All forms of pemphigus are associated with the presence of circulating and skin-fixed autoantibodies....

Full description

Saved in:
Bibliographic Details
Published inDermatology online journal Vol. 18; no. 10; p. 10
Main Authors Augusto de Oliveira, Marcio, Martins E Martins, Fabiana, Lourenço, Silvia, Gallottini, Marina, Ortega, Karem L
Format Journal Article
LanguageEnglish
Published United States 15.10.2012
Subjects
Adult
Chronic Disease
Fluorescent Antibody Technique, Direct
Humans
Immunohistochemistry
Inflammatory Bowel Diseases - complications
Male
Mouth Diseases - complications
Mouth Diseases - diagnosis
Mouth Diseases - metabolism
Oral Ulcer - diagnosis
Pemphigus - complications
Pemphigus - diagnosis
Pemphigus - metabolism
Online AccessGet full text

Cover

More Information
Summary:Pemphigus is a rare vesiculobullous autoimmune disease that exhibits blistering of the skin and oral cavity. It is caused by autoantibodies directed against antigens on the surface of keratinocytes. All forms of pemphigus are associated with the presence of circulating and skin-fixed autoantibodies. Pemphigus vegetans is a rare clinical variant of pemphigus vulgaris and comprises up to 5 percent of all pemphigus cases. In the following we present the oral presentation of pemphigus vegetans. We describe a 33-year-old man who was referred to our clinic complaining about mouth sores, tooth pain, and multiple pustules. During clinical exam we were able to recognize multiple pustules, ulcerated areas on the gingiva, and whitish mucosal plaques. Clinical, histopathological, and direct immunofluorescence findings were compatible with pemphigus vegetans.
Bibliography:ObjectType-Case Study-2
SourceType-Scholarly Journals-1
ObjectType-Feature-4
content type line 23
ObjectType-Report-1
ObjectType-Article-3
ISSN:1087-2108
1087-2108
DOI:10.5070/D394R8J8DR