Signaling through Ca 2+ Microdomains from Store-Operated CRAC Channels

• Published in: Cold Spring Harbor perspectives in biology Vol. 12; no. 7; p. a035097
• Main Authors: Barak, Pradeep, Parekh, Anant B
• Format: Journal Article
• Language: English
• Published: United States 01.07.2020

Calcium (Ca ) ion microdomains are subcellular regions of high Ca concentration that develop rapidly near open Ca channels in the plasma membrane or internal stores and generate local regions of high Ca concentration. These microdomains are remarkably versatile in that they activate a range of respo...