Clinical management of six cases of low-risk primary tonsillar non-Hodgkin´s lymphoma

CONTEXT: There have been many reports that favor aggressive systemic treatment with chemotherapy and radiotherapy, even for well-localized lymphomas, avoiding the need for tonsillectomy of the normal tonsil. CASE REPORT: We report six cases of primary tonsillar lymphoma with a median patient age of...

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Published inSão Paulo medical journal Vol. 117; no. 5; pp. 215 - 217
Main Authors Colleoni, Gisele Wally Braga, Oliveira, José Salvador Rodrigues, Alves, Antonio Correa, Borducchi, Davimar Miranda Maciel, Segreto, Roberto Araújo, Cervantes, Onivaldo, Kerbauy, José
Format Journal Article
LanguageEnglish
Portuguese
Published Associação Paulista de Medicina - APM 01.09.1999
Associação Paulista de Medicina
Subjects
MEDICINE, GENERAL & INTERNAL
Non-Hodgkin´s lymphoma
Prognosis
Tonsil
Treatment
Linfoma não-Hodgkin
Treatment
Prognosis
Tonsil
Tratamento prognóstico
Tonsila palatina
Non-Hodgkin´s lymphoma
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Summary:CONTEXT: There have been many reports that favor aggressive systemic treatment with chemotherapy and radiotherapy, even for well-localized lymphomas, avoiding the need for tonsillectomy of the normal tonsil. CASE REPORT: We report six cases of primary tonsillar lymphoma with a median patient age of 42 years. There were two lymphoma cases with diffuse large cells, two cases with mixed small and large cells, one with small cells and one indeterminate. They were treated with six cycles of chemotherapy and cervical radiotherapy. All patients achieved durable complete remission. Our data agree with previous reports that suggested that primary tonsillar high-grade B-cell NHL has a good prognosis if aggressively treated. CONTEXTO: Muitos trabalhos têm proposto tratamento sistêmico agressivo com quimioterapia e radioterapia para os linfomas de tonsila palatina, mesmo tratando-se de tumores bem localizados, sem a necessidade de amidalectomia contralateral. RELATO DE CASO: Nós relatamos seis casos de linfoma primário de tonsila palatina, com idade mediana de 42 anos. Havia dois casos de linfoma difuso de grandes células, dois casos de linfoma de pequenas e grandes células, um caso de linfoma linfocítico de pequenas células e um caso indeterminado. Foram tratados com seis ciclos de quimioterapia e radioterapia cervical. Todos os pacientes atingiram remisão completa mantida. Nossos dados estão de acordo com relatos prévios que sugerem que os linfomas de células B têm bom prognóstico se agressivamente tratados.
ISSN:1516-3180
1806-9460
1516-3180
1806-9460
DOI:10.1590/S1516-31801999000500006