Self‐Assembly: Programmable Construction of Peptide‐Based Materials in Living Subjects: From Modular Design and Morphological Control to Theranostics (Adv. Mater. 45/2019)

The strategy of “in vivo self‐assembly”, which is defined as in situ construction of functional nanomaterials in living subjects to explore new biological effects, is summarized by Zeng‐Ying Qiao, Lei Wang, Hao Wang, and Li‐Li Li in article number 1804971. The modular design platform automatic sense...

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Published inAdvanced materials (Weinheim) Vol. 31; no. 45
Main Authors Li, Li‐Li, Qiao, Zeng‐Ying, Wang, Lei, Wang, Hao
Format Journal Article
LanguageEnglish
Published Weinheim Wiley Subscription Services, Inc 01.11.2019
Subjects
Assembly
bioimaging
Biological effects
drug delivery
Drug delivery systems
Functional materials
Materials science
Medical imaging
Modular construction
Modular design
Nanomaterials
peptides
programmable
self‐assembly
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Summary:The strategy of “in vivo self‐assembly”, which is defined as in situ construction of functional nanomaterials in living subjects to explore new biological effects, is summarized by Zeng‐Ying Qiao, Lei Wang, Hao Wang, and Li‐Li Li in article number 1804971. The modular design platform automatic senses the targeting physiological microenvironment and constructs defined nanostructures in vivo. These dynamically assembled delivery platforms exhibit the assembly/aggregation‐induced retention (AIR) effect, resulting in an enhanced targeting efficiency, which will further be applied in clinical high‐performance drug delivery and bioimaging.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
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ISSN:0935-9648
1521-4095
DOI:10.1002/adma.201970321