Measurement of attenuation coefficient using ultrasound-guided attenuation parameter for evaluation of fatty liver

• Published in: Kanzo Vol. 59; no. 3; pp. 194 - 196
• Main Authors: Tada, Toshifumi, Kumada, Takashi, Toyoda, Hidenori, Hashinokuchi, Shinichi, Ogawa, Sadanobu, Oguri, Takuma, Kamiyama, Naohisa
• Format: Journal Article
• Language: Japanese; English
• Published: The Japan Society of Hepatology 2018
• Subjects: fatty liver; proton density fat fraction; ultrasound-guided attenuation parameter
• ISSN: 0451-4203; 1881-3593
• DOI: 10.2957/kanzo.59.194

We evaluated the attenuation coefficient (AC) using ultrasound-guided attenuation parameter (UGAP) for diagnosis of fatty liver. In the correlation analysis between AC values and magnetic resonance-based proton density fat fraction (PDFF) values, the correlation coefficient was 0.79, corresponding to a strong relationship. The area under the receiver operating characteristic curve for diagnosis of steatosis grade (≥1, ≥2, 3) based on the PDFF values were, 0.93, 0.92, and 0.91, respectively, corresponding to high diagnostic values. Even though, in the patients with more than 25 kg/m2 of body mass index, the correlation coefficient between AC values and PDFF values was 0.81. In conclusion, the measurement of AC using UGAP as a non-invasive method is useful for quantitative evaluation of fatty liver.