Uptake of 18F-Fluciclovine in Paget Disease
Since its recent approval by the United States Food and Drug Administration, fluciclovine PET-CT has gained widespread use for imaging of recurrent prostate cancer patients. As an amino acid-based radiotracer transported by LAT-1 and ASCT-2 transporters, fluciclovine exploits the up-regulation of am...
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Published in | Clinical nuclear medicine |
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Main Authors | , , |
Format | Journal Article |
Language | English |
Published |
United States
01.11.2019
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Online Access | Get more information |
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Summary: | Since its recent approval by the United States Food and Drug Administration, fluciclovine PET-CT has gained widespread use for imaging of recurrent prostate cancer patients. As an amino acid-based radiotracer transported by LAT-1 and ASCT-2 transporters, fluciclovine exploits the up-regulation of amino acid transporters in malignant cells. We present a rare case of fluciclovine uptake in Paget disease in a 58-year-old man with suspected recurrent prostate cancer and asymmetric increased left hemipelvic uptake on imaging. |
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ISSN: | 1536-0229 |
DOI: | 10.1097/RLU.0000000000002670 |